diff --git a/src/core/cdrom.cpp b/src/core/cdrom.cpp
index ce69f7b26..e7201c732 100644
--- a/src/core/cdrom.cpp
+++ b/src/core/cdrom.cpp
@@ -424,6 +424,12 @@ void CDROM::SetAsyncInterrupt(Interrupt interrupt)
     DeliverAsyncInterrupt();
 }
 
+void CDROM::CancelAsyncInterrupt()
+{
+  m_pending_async_interrupt = 0;
+  m_async_response_fifo.Clear();
+}
+
 void CDROM::DeliverAsyncInterrupt()
 {
   Assert(m_pending_async_interrupt != 0 && !HasPendingInterrupt());
@@ -992,6 +998,7 @@ void CDROM::DoSectorRead()
   if (HasPendingAsyncInterrupt())
   {
     Log_WarningPrintf("Data interrupt was not delivered");
+    CancelAsyncInterrupt();
   }
   if (!m_sector_buffer.empty())
   {
diff --git a/src/core/cdrom.h b/src/core/cdrom.h
index 9e980e5c8..cb9dbae4f 100644
--- a/src/core/cdrom.h
+++ b/src/core/cdrom.h
@@ -171,6 +171,7 @@ private:
   bool HasPendingAsyncInterrupt() const { return m_pending_async_interrupt != 0; }
   void SetInterrupt(Interrupt interrupt);
   void SetAsyncInterrupt(Interrupt interrupt);
+  void CancelAsyncInterrupt();
   void DeliverAsyncInterrupt();
   void SendACKAndStat();
   void SendErrorResponse(u8 reason = 0x80);