diff --git a/src/duckstation-qt/gamepropertiesdialog.cpp b/src/duckstation-qt/gamepropertiesdialog.cpp
index c41946b54..c62067b2e 100644
--- a/src/duckstation-qt/gamepropertiesdialog.cpp
+++ b/src/duckstation-qt/gamepropertiesdialog.cpp
@@ -132,6 +132,13 @@ void GamePropertiesDialog::setupAdditionalUi()
       qApp->translate("DisplayCropMode", Settings::GetDisplayCropModeDisplayName(static_cast<DisplayCropMode>(i))));
   }
 
+  m_ui.userDownsampleMode->addItem(tr("(unchanged)"));
+  for (u32 i = 0; i < static_cast<u32>(GPUDownsampleMode::Count); i++)
+  {
+    m_ui.userDownsampleMode->addItem(
+      qApp->translate("GPUDownsampleMode", Settings::GetDownsampleModeDisplayName(static_cast<GPUDownsampleMode>(i))));
+  }
+
   m_ui.userResolutionScale->addItem(tr("(unchanged)"));
   QtUtils::FillComboBoxWithResolutionScales(m_ui.userResolutionScale);
 
@@ -341,6 +348,11 @@ void GamePropertiesDialog::populateGameSettings()
     QSignalBlocker sb(m_ui.userAspectRatio);
     m_ui.userAspectRatio->setCurrentIndex(static_cast<int>(gs.display_aspect_ratio.value()) + 1);
   }
+  if (gs.gpu_downsample_mode.has_value())
+  {
+    QSignalBlocker sb(m_ui.userDownsampleMode);
+    m_ui.userDownsampleMode->setCurrentIndex(static_cast<int>(gs.gpu_downsample_mode.value()) + 1);
+  }
 
   populateBooleanUserSetting(m_ui.userLinearUpscaling, gs.display_linear_upscaling);
   populateBooleanUserSetting(m_ui.userIntegerUpscaling, gs.display_integer_upscaling);
@@ -525,6 +537,14 @@ void GamePropertiesDialog::connectUi()
     saveGameSettings();
   });
 
+  connect(m_ui.userDownsampleMode, QOverload<int>::of(&QComboBox::currentIndexChanged), [this](int index) {
+    if (index <= 0)
+      m_game_settings.gpu_downsample_mode.reset();
+    else
+      m_game_settings.gpu_downsample_mode = static_cast<GPUDownsampleMode>(index - 1);
+    saveGameSettings();
+  });
+
   connectBooleanUserSetting(m_ui.userLinearUpscaling, &m_game_settings.display_linear_upscaling);
   connectBooleanUserSetting(m_ui.userIntegerUpscaling, &m_game_settings.display_integer_upscaling);
 
diff --git a/src/duckstation-qt/gamepropertiesdialog.ui b/src/duckstation-qt/gamepropertiesdialog.ui
index 5fe8cb6f2..09118dd3b 100644
--- a/src/duckstation-qt/gamepropertiesdialog.ui
+++ b/src/duckstation-qt/gamepropertiesdialog.ui
@@ -281,7 +281,17 @@
           <item row="1" column="1">
            <widget class="QComboBox" name="userCropMode"/>
           </item>
-          <item row="2" column="0" colspan="2">
+          <item row="2" column="0">
+           <widget class="QLabel" name="label_31">
+            <property name="text">
+             <string>Downsampling:</string>
+            </property>
+           </widget>
+          </item>
+          <item row="2" column="1">
+           <widget class="QComboBox" name="userDownsampleMode"/>
+          </item>
+          <item row="3" column="0" colspan="2">
            <layout class="QGridLayout" name="gridLayout_2">
             <item row="0" column="0">
              <widget class="QCheckBox" name="userLinearUpscaling">
diff --git a/src/frontend-common/game_list.h b/src/frontend-common/game_list.h
index 04de7479e..2122c5c7f 100644
--- a/src/frontend-common/game_list.h
+++ b/src/frontend-common/game_list.h
@@ -108,7 +108,7 @@ private:
   enum : u32
   {
     GAME_LIST_CACHE_SIGNATURE = 0x45434C47,
-    GAME_LIST_CACHE_VERSION = 19
+    GAME_LIST_CACHE_VERSION = 20
   };
 
   using DatabaseMap = std::unordered_map<std::string, GameListDatabaseEntry>;
diff --git a/src/frontend-common/game_settings.cpp b/src/frontend-common/game_settings.cpp
index ec3764328..193fbf642 100644
--- a/src/frontend-common/game_settings.cpp
+++ b/src/frontend-common/game_settings.cpp
@@ -119,6 +119,7 @@ bool Entry::LoadFromStream(ByteStream* stream)
       !ReadOptionalFromStream(stream, &gpu_pgxp_tolerance) ||
       !ReadOptionalFromStream(stream, &gpu_pgxp_depth_threshold) ||
       !ReadOptionalFromStream(stream, &display_crop_mode) || !ReadOptionalFromStream(stream, &display_aspect_ratio) ||
+      !ReadOptionalFromStream(stream, &gpu_downsample_mode) ||
       !ReadOptionalFromStream(stream, &display_linear_upscaling) ||
       !ReadOptionalFromStream(stream, &display_integer_upscaling) ||
       !ReadOptionalFromStream(stream, &display_force_4_3_for_24bit) ||
@@ -167,7 +168,7 @@ bool Entry::SaveToStream(ByteStream* stream) const
          WriteOptionalToStream(stream, dma_halt_ticks) && WriteOptionalToStream(stream, gpu_fifo_size) &&
          WriteOptionalToStream(stream, gpu_max_run_ahead) && WriteOptionalToStream(stream, gpu_pgxp_tolerance) &&
          WriteOptionalToStream(stream, gpu_pgxp_depth_threshold) && WriteOptionalToStream(stream, display_crop_mode) &&
-         WriteOptionalToStream(stream, display_aspect_ratio) &&
+         WriteOptionalToStream(stream, display_aspect_ratio) && WriteOptionalToStream(stream, gpu_downsample_mode) &&
          WriteOptionalToStream(stream, display_linear_upscaling) &&
          WriteOptionalToStream(stream, display_integer_upscaling) &&
          WriteOptionalToStream(stream, display_force_4_3_for_24bit) &&
@@ -243,6 +244,9 @@ static void ParseIniSection(Entry* entry, const char* section, const CSimpleIniA
   cvalue = ini.GetValue(section, "DisplayAspectRatio", nullptr);
   if (cvalue)
     entry->display_aspect_ratio = Settings::ParseDisplayAspectRatio(cvalue);
+  cvalue = ini.GetValue(section, "GPUDownsampleMode", nullptr);
+  if (cvalue)
+    entry->gpu_downsample_mode = Settings::ParseDownsampleModeName(cvalue);
   cvalue = ini.GetValue(section, "DisplayLinearUpscaling", nullptr);
   if (cvalue)
     entry->display_linear_upscaling = StringUtil::FromChars<bool>(cvalue);
@@ -354,6 +358,10 @@ static void StoreIniSection(const Entry& entry, const char* section, CSimpleIniA
     ini.SetValue(section, "DisplayAspectRatio",
                  Settings::GetDisplayAspectRatioName(entry.display_aspect_ratio.value()));
   }
+  if (entry.gpu_downsample_mode.has_value())
+  {
+    ini.SetValue(section, "GPUDownsampleMode", Settings::GetDownsampleModeName(entry.gpu_downsample_mode.value()));
+  }
   if (entry.display_linear_upscaling.has_value())
     ini.SetValue(section, "DisplayLinearUpscaling", entry.display_linear_upscaling.value() ? "true" : "false");
   if (entry.display_integer_upscaling.has_value())
@@ -536,6 +544,8 @@ void Entry::ApplySettings(bool display_osd_messages) const
     g_settings.display_crop_mode = display_crop_mode.value();
   if (display_aspect_ratio.has_value())
     g_settings.display_aspect_ratio = display_aspect_ratio.value();
+  if (gpu_downsample_mode.has_value())
+    g_settings.gpu_downsample_mode = gpu_downsample_mode.value();
   if (display_linear_upscaling.has_value())
     g_settings.display_linear_filtering = display_linear_upscaling.value();
   if (display_integer_upscaling.has_value())
diff --git a/src/frontend-common/game_settings.h b/src/frontend-common/game_settings.h
index 9155adbc3..6b61cf43b 100644
--- a/src/frontend-common/game_settings.h
+++ b/src/frontend-common/game_settings.h
@@ -56,6 +56,7 @@ struct Entry
   std::optional<u32> cdrom_read_speedup;
   std::optional<DisplayCropMode> display_crop_mode;
   std::optional<DisplayAspectRatio> display_aspect_ratio;
+  std::optional<GPUDownsampleMode> gpu_downsample_mode;
   std::optional<bool> display_linear_upscaling;
   std::optional<bool> display_integer_upscaling;
   std::optional<bool> display_force_4_3_for_24bit;