diff --git a/src/core/host_interface.cpp b/src/core/host_interface.cpp
index 40f83ce40..86af9b33e 100644
--- a/src/core/host_interface.cpp
+++ b/src/core/host_interface.cpp
@@ -776,6 +776,7 @@ void HostInterface::SetDefaultSettings()
   m_settings.increase_timer_resolution = true;
   m_settings.start_paused = false;
   m_settings.save_state_on_exit = true;
+  m_settings.confim_power_off = true;
 
   m_settings.gpu_renderer = Settings::DEFAULT_GPU_RENDERER;
   m_settings.gpu_resolution_scale = 1;
diff --git a/src/core/settings.cpp b/src/core/settings.cpp
index 170638cef..b0ffbe0c7 100644
--- a/src/core/settings.cpp
+++ b/src/core/settings.cpp
@@ -14,6 +14,7 @@ void Settings::Load(SettingsInterface& si)
   increase_timer_resolution = si.GetBoolValue("General", "IncreaseTimerResolution", true);
   start_paused = si.GetBoolValue("General", "StartPaused", false);
   save_state_on_exit = si.GetBoolValue("General", "SaveStateOnExit", true);
+  confim_power_off = si.GetBoolValue("General", "ConfirmPowerOff", true);
 
   cpu_execution_mode = ParseCPUExecutionMode(si.GetStringValue("CPU", "ExecutionMode", "Interpreter").c_str())
                          .value_or(CPUExecutionMode::Interpreter);
@@ -67,6 +68,7 @@ void Settings::Save(SettingsInterface& si) const
   si.SetBoolValue("General", "IncreaseTimerResolution", increase_timer_resolution);
   si.SetBoolValue("General", "StartPaused", start_paused);
   si.SetBoolValue("General", "SaveStateOnExit", save_state_on_exit);
+  si.SetBoolValue("General", "ConfirmPowerOff", confim_power_off);
 
   si.SetStringValue("CPU", "ExecutionMode", GetCPUExecutionModeName(cpu_execution_mode));
 
diff --git a/src/core/settings.h b/src/core/settings.h
index 7546b960f..9f5e62903 100644
--- a/src/core/settings.h
+++ b/src/core/settings.h
@@ -40,6 +40,7 @@ struct Settings
   bool increase_timer_resolution = true;
   bool start_paused = false;
   bool save_state_on_exit = true;
+  bool confim_power_off = true;
 
   GPURenderer gpu_renderer = GPURenderer::Software;
   u32 gpu_resolution_scale = 1;
diff --git a/src/duckstation-qt/consolesettingswidget.cpp b/src/duckstation-qt/consolesettingswidget.cpp
index 0a2db08d3..feb0cc768 100644
--- a/src/duckstation-qt/consolesettingswidget.cpp
+++ b/src/duckstation-qt/consolesettingswidget.cpp
@@ -28,6 +28,7 @@ ConsoleSettingsWidget::ConsoleSettingsWidget(QtHostInterface* host_interface, QW
                                                      100.0f);
   SettingWidgetBinder::BindWidgetToBoolSetting(m_host_interface, m_ui.pauseOnStart, "General/StartPaused");
   SettingWidgetBinder::BindWidgetToBoolSetting(m_host_interface, m_ui.saveStateOnExit, "General/SaveStateOnExit");
+  SettingWidgetBinder::BindWidgetToBoolSetting(m_host_interface, m_ui.confirmPowerOff, "General/ConfirmPowerOff");
   SettingWidgetBinder::BindWidgetToEnumSetting(m_host_interface, m_ui.cpuExecutionMode, "CPU/ExecutionMode",
                                                &Settings::ParseCPUExecutionMode, &Settings::GetCPUExecutionModeName);
   SettingWidgetBinder::BindWidgetToBoolSetting(m_host_interface, m_ui.cdromReadThread, "CDROM/ReadThread");
diff --git a/src/duckstation-qt/consolesettingswidget.ui b/src/duckstation-qt/consolesettingswidget.ui
index d6e528b9c..2f4e65ed9 100644
--- a/src/duckstation-qt/consolesettingswidget.ui
+++ b/src/duckstation-qt/consolesettingswidget.ui
@@ -160,6 +160,13 @@
         </property>
        </widget>
       </item>
+      <item row="8" column="0" colspan="2">
+       <widget class="QCheckBox" name="confirmPowerOff">
+        <property name="text">
+         <string>Confirm Power Off</string>
+        </property>
+       </widget>
+      </item>
      </layout>
     </widget>
    </item>
diff --git a/src/duckstation-qt/qthostinterface.cpp b/src/duckstation-qt/qthostinterface.cpp
index 79b810d75..64d1629c3 100644
--- a/src/duckstation-qt/qthostinterface.cpp
+++ b/src/duckstation-qt/qthostinterface.cpp
@@ -433,6 +433,7 @@ std::vector<QtHostInterface::HotkeyInfo> QtHostInterface::getHotkeyList() const
     {QStringLiteral("FastForward"), QStringLiteral("Toggle Fast Forward"), QStringLiteral("General")},
     {QStringLiteral("Fullscreen"), QStringLiteral("Toggle Fullscreen"), QStringLiteral("General")},
     {QStringLiteral("Pause"), QStringLiteral("Toggle Pause"), QStringLiteral("General")},
+    {QStringLiteral("PowerOff"), QStringLiteral("Power Off System"), QStringLiteral("General")},
     {QStringLiteral("ToggleSoftwareRendering"), QStringLiteral("Toggle Software Rendering"),
      QStringLiteral("Graphics")},
     {QStringLiteral("IncreaseResolutionScale"), QStringLiteral("Increase Resolution Scale"),
@@ -486,6 +487,36 @@ void QtHostInterface::updateHotkeyInputMap()
       pauseSystem(!m_paused);
   });
 
+  hk(QStringLiteral("PowerOff"), [this](bool pressed) {
+    if (!pressed && m_system)
+    {
+      if (m_settings.confim_power_off)
+      {
+        emit setFullscreenRequested(false);
+
+        QString confirmation_message = tr("Are you sure you want to stop emulation?");
+        if (m_settings.save_state_on_exit)
+        {
+          confirmation_message += "\n\n";
+          confirmation_message += tr("The current state will be saved.");
+        }
+
+        if (!messageConfirmed(confirmation_message))
+        {
+          if (m_settings.display_fullscreen)
+            emit setFullscreenRequested(true);
+          else
+            emit focusDisplayWidgetRequested();
+
+          m_system->ResetPerformanceCounters();
+          return;
+        }
+      }
+
+      powerOffSystem();
+    }
+  });
+
   hk(QStringLiteral("ToggleSoftwareRendering"), [this](bool pressed) {
     if (!pressed)
       ToggleSoftwareRendering();
@@ -655,6 +686,9 @@ void QtHostInterface::pauseSystem(bool paused)
     return;
   }
 
+  if (!m_system)
+    return;
+
   m_paused = paused;
   m_audio_stream->PauseOutput(paused);
   if (!paused)