diff --git a/src/duckstation-qt/debuggerwindow.cpp b/src/duckstation-qt/debuggerwindow.cpp
index 9247b371b..1f6115bb7 100644
--- a/src/duckstation-qt/debuggerwindow.cpp
+++ b/src/duckstation-qt/debuggerwindow.cpp
@@ -15,6 +15,8 @@
 #include <QtWidgets/QFileDialog>
 #include <QtWidgets/QMessageBox>
 
+static constexpr int TIMER_REFRESH_INTERVAL_MS = 100;
+
 DebuggerWindow::DebuggerWindow(QWidget* parent /* = nullptr */)
   : QMainWindow(parent), m_active_memory_region(Bus::MemoryRegion::Count)
 {
@@ -64,11 +66,16 @@ void DebuggerWindow::onDebuggerMessageReported(const QString& message)
   m_ui.statusbar->showMessage(message, 0);
 }
 
+void DebuggerWindow::timerRefresh()
+{
+  m_ui.memoryView->forceRefresh();
+}
+
 void DebuggerWindow::refreshAll()
 {
   m_registers_model->updateValues();
   m_stack_model->invalidateView();
-  m_ui.memoryView->repaint();
+  m_ui.memoryView->forceRefresh();
 
   m_code_model->setPC(CPU::g_state.pc);
   scrollToPC();
@@ -478,6 +485,9 @@ void DebuggerWindow::connectSignals()
 
   connect(m_ui.memorySearch, &QPushButton::clicked, this, &DebuggerWindow::onMemorySearchTriggered);
   connect(m_ui.memorySearchString, &QLineEdit::textChanged, this, &DebuggerWindow::onMemorySearchStringChanged);
+
+  connect(&m_refresh_timer, &QTimer::timeout, this, &DebuggerWindow::timerRefresh);
+  m_refresh_timer.setInterval(TIMER_REFRESH_INTERVAL_MS);
 }
 
 void DebuggerWindow::disconnectSignals()
@@ -514,28 +524,35 @@ void DebuggerWindow::createModels()
 
 void DebuggerWindow::setUIEnabled(bool enabled, bool allow_pause)
 {
+  const bool memory_view_enabled = (enabled || allow_pause);
+
   m_ui.actionPause->setEnabled(allow_pause);
 
   // Disable all UI elements that depend on execution state
   m_ui.codeView->setEnabled(enabled);
   m_ui.registerView->setEnabled(enabled);
   m_ui.stackView->setEnabled(enabled);
-  m_ui.memoryView->setEnabled(enabled);
+  m_ui.memoryView->setEnabled(memory_view_enabled);
   m_ui.actionRunToCursor->setEnabled(enabled);
   m_ui.actionAddBreakpoint->setEnabled(enabled);
   m_ui.actionToggleBreakpoint->setEnabled(enabled);
   m_ui.actionClearBreakpoints->setEnabled(enabled);
-  m_ui.actionDumpAddress->setEnabled(enabled);
+  m_ui.actionDumpAddress->setEnabled(memory_view_enabled);
   m_ui.actionStepInto->setEnabled(enabled);
   m_ui.actionStepOver->setEnabled(enabled);
   m_ui.actionStepOut->setEnabled(enabled);
   m_ui.actionGoToAddress->setEnabled(enabled);
   m_ui.actionGoToPC->setEnabled(enabled);
   m_ui.actionTrace->setEnabled(enabled);
-  m_ui.memoryRegionRAM->setEnabled(enabled);
-  m_ui.memoryRegionEXP1->setEnabled(enabled);
-  m_ui.memoryRegionScratchpad->setEnabled(enabled);
-  m_ui.memoryRegionBIOS->setEnabled(enabled);
+  m_ui.memoryRegionRAM->setEnabled(memory_view_enabled);
+  m_ui.memoryRegionEXP1->setEnabled(memory_view_enabled);
+  m_ui.memoryRegionScratchpad->setEnabled(memory_view_enabled);
+  m_ui.memoryRegionBIOS->setEnabled(memory_view_enabled);
+
+  // Partial/timer refreshes only active when not paused.
+  const bool timer_active = (!enabled && allow_pause);
+  if (m_refresh_timer.isActive() != timer_active)
+    timer_active ? m_refresh_timer.start() : m_refresh_timer.stop();
 }
 
 void DebuggerWindow::saveCurrentState()
diff --git a/src/duckstation-qt/debuggerwindow.h b/src/duckstation-qt/debuggerwindow.h
index 571affe14..61aef9375 100644
--- a/src/duckstation-qt/debuggerwindow.h
+++ b/src/duckstation-qt/debuggerwindow.h
@@ -8,6 +8,7 @@
 #include "core/cpu_core.h"
 #include "core/types.h"
 
+#include <QtCore/QTimer>
 #include <QtWidgets/QMainWindow>
 #include <memory>
 #include <optional>
@@ -41,6 +42,7 @@ private Q_SLOTS:
   void onSystemResumed();
   void onDebuggerMessageReported(const QString& message);
 
+  void timerRefresh();
   void refreshAll();
 
   void scrollToPC();
@@ -89,6 +91,8 @@ private:
   std::unique_ptr<DebuggerRegistersModel> m_registers_model;
   std::unique_ptr<DebuggerStackModel> m_stack_model;
 
+  QTimer m_refresh_timer;
+
   Bus::MemoryRegion m_active_memory_region;
 
   PhysicalMemoryAddress m_next_memory_search_address = 0;
diff --git a/src/duckstation-qt/memoryviewwidget.cpp b/src/duckstation-qt/memoryviewwidget.cpp
index 8621982d1..5b4d5cbb1 100644
--- a/src/duckstation-qt/memoryviewwidget.cpp
+++ b/src/duckstation-qt/memoryviewwidget.cpp
@@ -125,7 +125,7 @@ void MemoryViewWidget::keyPressEvent(QKeyEvent* event)
       {
         m_selected_address--;
         m_editing_nibble = -1;
-        viewport()->update();
+        forceRefresh();
       }
     }
     else
@@ -139,7 +139,7 @@ void MemoryViewWidget::keyPressEvent(QKeyEvent* event)
           expandCurrentDataToInclude(m_selected_address);
           std::memcpy(static_cast<unsigned char*>(m_data) + m_selected_address, &ch, sizeof(unsigned char));
           m_selected_address = std::min(m_selected_address + 1, m_data_size - 1);
-          viewport()->update();
+          forceRefresh();
         }
         else
         {
@@ -165,7 +165,7 @@ void MemoryViewWidget::keyPressEvent(QKeyEvent* event)
               m_selected_address = std::min(m_selected_address + 1, m_data_size - 1);
             }
 
-            viewport()->update();
+            forceRefresh();
           }
         }
       }
@@ -381,7 +381,7 @@ void MemoryViewWidget::updateSelectedByte(const QPoint& pos)
     m_selected_address = new_selection;
     m_selection_was_ascii = new_ascii;
     m_editing_nibble = -1;
-    viewport()->update();
+    forceRefresh();
   }
 }
 
@@ -419,6 +419,11 @@ void MemoryViewWidget::saveCurrentData()
   m_last_data_start_offset = m_start_offset;
   m_last_data.resize(size);
   std::memcpy(m_last_data.data(), static_cast<const u8*>(m_data) + m_start_offset, size);
+  forceRefresh();
+}
+
+void MemoryViewWidget::forceRefresh()
+{
   viewport()->update();
 }
 
@@ -447,5 +452,8 @@ void MemoryViewWidget::adjustContent()
   verticalScrollBar()->setRange(0, lineCount - m_rows_visible);
   verticalScrollBar()->setPageStep(m_rows_visible);
 
-  viewport()->update();
+  expandCurrentDataToInclude(m_start_offset);
+  expandCurrentDataToInclude(m_end_offset);
+
+  forceRefresh();
 }
\ No newline at end of file
diff --git a/src/duckstation-qt/memoryviewwidget.h b/src/duckstation-qt/memoryviewwidget.h
index 1791fc469..2f6209bf6 100644
--- a/src/duckstation-qt/memoryviewwidget.h
+++ b/src/duckstation-qt/memoryviewwidget.h
@@ -34,6 +34,7 @@ protected:
 
 public Q_SLOTS:
   void saveCurrentData();
+  void forceRefresh();
 
 private Q_SLOTS:
   void adjustContent();