diff --git a/src/core/settings.cpp b/src/core/settings.cpp
index 619c7f0d6..0e6a84e14 100644
--- a/src/core/settings.cpp
+++ b/src/core/settings.cpp
@@ -908,11 +908,13 @@ const char* Settings::GetControllerTypeDisplayName(ControllerType type)
   return s_controller_display_names[static_cast<int>(type)];
 }
 
-static std::array<const char*, 4> s_memory_card_type_names = {{"None", "Shared", "PerGame", "PerGameTitle"}};
-static std::array<const char*, 4> s_memory_card_type_display_names = {
+static std::array<const char*, 5> s_memory_card_type_names = {
+  {"None", "Shared", "PerGame", "PerGameTitle", "PerGameFileTitle"}};
+static std::array<const char*, 5> s_memory_card_type_display_names = {
   {TRANSLATABLE("MemoryCardType", "No Memory Card"), TRANSLATABLE("MemoryCardType", "Shared Between All Games"),
    TRANSLATABLE("MemoryCardType", "Separate Card Per Game (Game Code)"),
-   TRANSLATABLE("MemoryCardType", "Separate Card Per Game (Game Title)")}};
+   TRANSLATABLE("MemoryCardType", "Separate Card Per Game (Game Title)"),
+   TRANSLATABLE("MemoryCardType", "Separate Card Per Game (File Title)")}};
 
 std::optional<MemoryCardType> Settings::ParseMemoryCardTypeName(const char* str)
 {
diff --git a/src/core/system.cpp b/src/core/system.cpp
index 12485712d..e29a0290f 100644
--- a/src/core/system.cpp
+++ b/src/core/system.cpp
@@ -1821,6 +1821,28 @@ void UpdateMemoryCards()
       }
       break;
 
+      case MemoryCardType::PerGameFileTitle:
+      {
+        const std::string display_name(FileSystem::GetDisplayNameFromPath(s_running_game_path));
+        const std::string_view file_title(FileSystem::GetFileTitleFromPath(display_name));
+        if (file_title.empty())
+        {
+          g_host_interface->AddFormattedOSDMessage(
+            5.0f,
+            g_host_interface->TranslateString("System",
+                                              "Per-game memory card cannot be used for slot %u as the running "
+                                              "game has no path. Using shared card instead."),
+            i + 1u);
+          card = MemoryCard::Open(g_host_interface->GetSharedMemoryCardPath(i));
+        }
+        else
+        {
+          card = MemoryCard::Open(
+            g_host_interface->GetGameMemoryCardPath(MemoryCard::SanitizeGameTitleForFileName(file_title).c_str(), i));
+        }
+      }
+      break;
+
       case MemoryCardType::Shared:
       {
         if (g_settings.memory_card_paths[i].empty())
diff --git a/src/core/types.h b/src/core/types.h
index 86709dbf1..9b5ca022b 100644
--- a/src/core/types.h
+++ b/src/core/types.h
@@ -134,6 +134,7 @@ enum class MemoryCardType
   Shared,
   PerGame,
   PerGameTitle,
+  PerGameFileTitle,
   Count
 };
 
diff --git a/src/duckstation-qt/qthostinterface.cpp b/src/duckstation-qt/qthostinterface.cpp
index d8226d6e5..1786bf075 100644
--- a/src/duckstation-qt/qthostinterface.cpp
+++ b/src/duckstation-qt/qthostinterface.cpp
@@ -1050,6 +1050,13 @@ void QtHostInterface::populateGameListContextMenu(const GameListEntry* entry, QW
           paths[i] = QString::fromStdString(
             GetGameMemoryCardPath(MemoryCard::SanitizeGameTitleForFileName(entry->title).c_str(), i));
           break;
+        case MemoryCardType::PerGameFileTitle:
+        {
+          const std::string display_name(FileSystem::GetDisplayNameFromPath(entry->path));
+          paths[i] = QString::fromStdString(GetGameMemoryCardPath(
+            MemoryCard::SanitizeGameTitleForFileName(FileSystem::GetFileTitleFromPath(display_name)).c_str(), i));
+        }
+        break;
         default:
           break;
       }